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Nasally delivered VEGFD mimetics mitigate stroke-induced dendrite loss and brain damage

In the adult brain, vascular endothelial growth factor D (VEGFD) is required for structural integrity of dendrites and cognitive abilities. Alterations of dendritic architectures are hallmarks of many neurologic disorders, including stroke-induced damage caused by toxic extrasynaptic NMDA receptor (...

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Mauceri, Daniela, Buchthal, Bettina, Hemstedt, Thekla J., Weiss, Ursula, Klein, Christian D., Bading, Hilmar
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7165430/
https://ncbi.nlm.nih.gov/pubmed/32229571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2001563117
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