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Merlin regulates signaling events at the nexus of development and cancer
BACKGROUND: In this review, we describe how the cytoskeletal protein Merlin, encoded by the Neurofibromin 2 (NF2) gene, orchestrates developmental signaling to ensure normal ontogeny, and we discuss how Merlin deficiency leads to aberrant activation of developmental pathways that enable tumor develo...
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| Pubblicato in: | Cell Commun Signal |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7164249/ https://ncbi.nlm.nih.gov/pubmed/32299434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00544-7 |
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