Deficiency of tumor suppressor Merlin facilitates metabolic adaptation by co-operative engagement of SMAD-Hippo signaling in breast cancer

The NF2 gene encodes the tumor and metastasis suppressor protein Merlin. Merlin exerts its tumor suppressive role by inhibiting proliferation and inducing contact-growth inhibition and apoptosis. In the current investigation, we determined that loss of Merlin in breast cancer tissues is concordant w...

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Detalhes bibliográficos
Publicado no:Carcinogenesis
Main Authors: Mota, Mateus S V, Jackson, William P, Bailey, Sarah K, Vayalil, Praveen, Landar, Aimee, Rostas, Jack W, Mulekar, Madhuri S, Samant, Rajeev S, Shevde, Lalita A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Carcinogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148973/
https://ncbi.nlm.nih.gov/pubmed/29893810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgy078
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