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An analysis of genetically regulated gene expression across multiple tissues implicates novel gene candidates in Alzheimer’s disease

INTRODUCTION: Genome-wide association studies (GWAS) have successfully identified multiple independent genetic loci that harbour variants associated with Alzheimer’s disease, but the exact causal genes and biological pathways are largely unknown. METHODS: To prioritise likely causal genes associated...

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Publicat a:Alzheimers Res Ther
Autors principals: Gerring, Zachary F., Lupton, Michelle K., Edey, Daniel, Gamazon, Eric R., Derks, Eske M.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164172/
https://ncbi.nlm.nih.gov/pubmed/32299494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-020-00611-8
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