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Multi-tissue transcriptome analyses identify genetic mechanisms underlying neuropsychiatric traits

The genetic architecture of psychiatric disorders is characterized by a large number of small-effect variants(1) located primarily in non-coding regions, suggesting that the underlying causal effects may influence disease risk by modulating gene expression(2–4). We provide comprehensive analyses usi...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Gamazon, Eric R., Zwinderman, Aeilko H., Cox, Nancy J., Denys, Damiaan, Derks, Eske M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590703/
https://ncbi.nlm.nih.gov/pubmed/31086352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-019-0409-8
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