Low-dose interleukin-2 alleviates dextran sodium sulfate-induced colitis in mice by recovering intestinal integrity and inhibiting AKT-dependent pathways

Several phase 1/2 clinical trials showed that low-dose interleukin-2 (IL-2) treatment is a safe and effective strategy for the treatment of chronic graft-versus-host disease, hepatitis C virus-induced vasculitis, and type 1 diabetes. Ulcerative colitis (UC) is a chronic inflammatory condition of the...

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Bibliografiske detaljer
Udgivet i:Theranostics
Main Authors: Lee, Hana, Son, Ye Seul, Lee, Mi-Ok, Ryu, Jea-Woon, Park, Kunhyang, Kwon, Ohman, Jung, Kwang Bo, Kim, Kwangho, Ryu, Tae Young, Baek, Aruem, Kim, Janghwan, Jung, Cho-Rok, Ryu, Choong-Min, Park, Young-Jun, Han, Tae-Su, Kim, Dae-Soo, Cho, Hyun-Soo, Son, Mi-Young
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7163458/
https://ncbi.nlm.nih.gov/pubmed/32308767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.41534
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