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Blockade of STAT3 Causes Severe In Vitro and In Vivo Maturation Defects in Intestinal Organoids Derived from Human Embryonic Stem Cells

Human intestinal organoids (hIOs), which resemble the human intestine structurally and physiologically, have emerged as a new modality for the study of the molecular and cellular biology of the intestine in vitro. We recently developed an in vitro maturation technique for generating functional hIOs...

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Dettagli Bibliografici
Pubblicato in:J Clin Med
Autori principali: Jung, Kwang Bo, Kwon, Ohman, Lee, Mi-Ok, Lee, Hana, Son, Ye Seul, Habib, Omer, Oh, Jung-Hwa, Cho, Hyun-Soo, Jung, Cho-Rok, Kim, Janghwan, Son, Mi-Young
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678857/
https://ncbi.nlm.nih.gov/pubmed/31277507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8070976
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