Interleukin-2 induces the in vitro maturation of human pluripotent stem cell-derived intestinal organoids

Human pluripotent stem cell (hPSC)-derived intestinal organoids (hIOs) form 3D structures organized into crypt and villus domains, making them an excellent in vitro model system for studying human intestinal development and disease. However, hPSC-derived hIOs still require in vivo maturation to full...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Jung, Kwang Bo, Lee, Hana, Son, Ye Seul, Lee, Mi-Ok, Kim, Young-Dae, Oh, Soo Jin, Kwon, Ohman, Cho, Sunwha, Cho, Hyun-Soo, Kim, Dae-Soo, Oh, Jung-Hwa, Zilbauer, Matthias, Min, Jeong-Ki, Jung, Cho-Rok, Kim, Janghwan, Son, Mi-Young
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072745/
https://ncbi.nlm.nih.gov/pubmed/30072687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05450-8
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