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Genetic variation in EPHA contributes to sensitivity to paclitaxel‐induced peripheral neuropathy
AIMS: Chemotherapy‐induced peripheral neuropathy (PN) is a treatment limiting toxicity of paclitaxel. We evaluated if EPHA genetic variation (EPHA4, EPHA5, EPHA6, and EPHA8) is associated with PN sensitivity by accounting for variability in systemic paclitaxel exposure (time above threshold). METHOD...
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| Publicado no: | Br J Clin Pharmacol |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7163383/ https://ncbi.nlm.nih.gov/pubmed/31823378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14192 |
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