CDDO-Me Alters the Tumor Microenvironment in Estrogen Receptor Negative Breast Cancer

The tumor microenvironment (TME) is an essential contributor to the development and progression of malignancy. Within the TME, tumor associated macrophages (TAMs) mediate angiogenesis, metastasis, and immunosuppression, which inhibits infiltration of tumor-specific cytotoxic CD8+ T cells. In previou...

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Udgivet i:Sci Rep
Main Authors: Ball, Michael S., Bhandari, Rajan, Torres, Gretel M., Martyanov, Viktor, ElTanbouly, Mohamed A., Archambault, Kim, Whitfield, Michael L., Liby, Karen T., Pioli, Patricia A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7162855/
https://ncbi.nlm.nih.gov/pubmed/32300202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63482-x
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