Pathological manifestation of the induced pluripotent stem cell‐derived cortical neurons from an early‐onset Alzheimer's disease patient carrying a presenilin‐1 mutation (S170F)

OBJECTIVES: Alzheimer's disease (AD) is the most common neurodegenerative disease which is characterized by the formation of amyloid beta (Aβ) plaques and neurofibrillary tangles. These abnormal proteins induce disturbance in mitochondrial dynamics and defect in autophagy system. Since presenil...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Li, Ling, Kim, Hee Jin, Roh, Jee Hoon, Kim, Minchul, Koh, Wonyoung, Kim, Younghoon, Heo, Hyohoon, Chung, Jaehoon, Nakanishi, Mahito, Yoon, Taeyoung, Hong, Chang Pyo, Seo, Sang Won, Na, Duk L., Song, Jihwan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7162796/
https://ncbi.nlm.nih.gov/pubmed/32216003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12798
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