iPSC Modeling of Presenilin1 Mutation in Alzheimer's Disease with Cerebellar Ataxia

Disease modeling of Alzheimer's disease (AD) has been hampered by the lack of suitable cellular models while animal models are mainly based on the overexpression of AD-related genes which often results in an overemphasis of certain pathways and is also confounded by aging. In this study, we the...

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Detalhes bibliográficos
Publicado no:Exp Neurobiol
Main Authors: Li, Ling, Roh, Jee Hoon, Chang, Eun Hyuk, Lee, Yoonkyung, Lee, Suji, Kim, Minchul, Koh, Wonyoung, Chang, Jong Wook, Kim, Hee Jin, Nakanishi, Mahito, Barker, Roger A., Na, Duk L., Song, Jihwan
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society for Brain and Neural Science 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6221836/
https://ncbi.nlm.nih.gov/pubmed/30429645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5607/en.2018.27.5.350
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