iPSC Modeling of Presenilin1 Mutation in Alzheimer's Disease with Cerebellar Ataxia

Disease modeling of Alzheimer's disease (AD) has been hampered by the lack of suitable cellular models while animal models are mainly based on the overexpression of AD-related genes which often results in an overemphasis of certain pathways and is also confounded by aging. In this study, we the...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Exp Neurobiol
Päätekijät: Li, Ling, Roh, Jee Hoon, Chang, Eun Hyuk, Lee, Yoonkyung, Lee, Suji, Kim, Minchul, Koh, Wonyoung, Chang, Jong Wook, Kim, Hee Jin, Nakanishi, Mahito, Barker, Roger A., Na, Duk L., Song, Jihwan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Korean Society for Brain and Neural Science 2018
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6221836/
https://ncbi.nlm.nih.gov/pubmed/30429645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5607/en.2018.27.5.350
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