Doxorubicin induces large-scale and differential H2A and H2B redistribution in live cells

We observed prominent effects of doxorubicin (Dox), an anthracycline widely used in anti-cancer therapy, on the aggregation and intracellular distribution of both partners of the H2A-H2B dimer, with marked differences between the two histones. Histone aggregation, assessed by Laser Scanning Cytometr...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Nánási, Péter, Imre, László, Firouzi Niaki, Erfaneh, Bosire, Rosevalentine, Mocsár, Gábor, Türk-Mázló, Anett, Ausio, Juan, Szabó, Gábor
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7162453/
https://ncbi.nlm.nih.gov/pubmed/32298286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0231223
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