Intercalation of small molecules into DNA in chromatin is primarily controlled by superhelical constraint

The restricted access of regulatory factors to their binding sites on DNA wrapped around the nucleosomes is generally interpreted in terms of molecular shielding exerted by nucleosomal structure and internucleosomal interactions. Binding of proteins to DNA often includes intercalation of hydrophobic...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bosire, Rosevalentine, Nánási, Péter, Imre, László, Dienes, Beatrix, Szöőr, Árpád, Mázló, Anett, Kovács, Attila, Seidel, Ralf, Vámosi, György, Szabó, Gábor
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6867626/
https://ncbi.nlm.nih.gov/pubmed/31747397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224936
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