Functional Differences Between EBV- and CMV-Specific CD8(+) T cells Demonstrate Heterogeneity of T cell Dysfunction in CLL

Acquired T cell dysfunction is a hallmark of chronic lymphocytic leukemia (CLL), and is linked to an increased risk of infections, but also reduced immune surveillance and disappointing responses to autologous T cell-based immunotherapy. The mechanisms of T cell dysfunction in CLL are not well under...

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Опубликовано в: :Hemasphere
Главные авторы: Hofland, Tom, de Weerdt, Iris, Endstra, Sanne, Jongejan, Aldo, Platenkamp, Laura, Remmerswaal, Ester B.M., Moerland, Perry D., ten Berge, Ineke J.M., Levin, Mark-David, Kater, Arnon P., Tonino, Sanne H.
Формат: Artigo
Язык:Inglês
Опубликовано: Wolters Kluwer Health 2020
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7162091/
https://ncbi.nlm.nih.gov/pubmed/32309780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HS9.0000000000000337
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