Natural Killer Cell Hypo-responsiveness in Chronic Lymphocytic Leukemia can be Circumvented In Vitro by Adequate Activating Signaling

Chronic lymphocytic leukemia (CLL) is characterized by an acquired immune dysfunction, which may underlie the hampered efficacy of cellular immunotherapy. Most data on dampened immune responses in CLL come from studies investigating CLL and T cell interactions. Natural killer (NK) cells may be an at...

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Publicado en:Hemasphere
Autores principales: Hofland, Tom, Endstra, Sanne, Gomes, Calum K.P., de Boer, Renate, de Weerdt, Iris, Bobkov, Vladimir, Riedl, Jurgen A., Heukers, Raimond, Smit, Martine J., Eldering, Eric, Levin, Mark-David, Kater, Arnon P., Tonino, Sanne H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Wolters Kluwer Health 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6924557/
https://ncbi.nlm.nih.gov/pubmed/31976482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HS9.0000000000000308
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