Human CXCR5(+)PD‐1(+) CD8 T cells in healthy individuals and patients with hematologic malignancies

Immune checkpoint blockade (ICB) has revolutionized cancer therapy, but varying response rates illustrate the need for biomarkers of response. Studies in mice have identified a subset of CD8 T cells that is essential for response to PD‐1 ICB. These CD8 T cells co‐express CXCR5, PD‐1 and Tcf1, and pr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Hofland, Tom, Martens, Anne W.J., van Bruggen, Jaco A.C., de Boer, Renate, Schetters, Sjoerd, Remmerswaal, Ester B.M., Bemelman, Frederike J., Levin, Mark‐David, Bins, Adriaan D., Eldering, Eric, Kater, Arnon P., Tonino, Sanne H.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Tumor immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7984320/
https://ncbi.nlm.nih.gov/pubmed/33098668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.202048761
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados