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Beyond DNA Damage: Exploring the Immunomodulatory Effects of Cyclophosphamide in Multiple Myeloma

The alkylating agent cyclophosphamide has been used in the treatment of multiple myeloma for over 60 years. At low doses, cyclophosphamide also has significant immunomodulatory activity, which can be used to modify the immunosuppressive tumor microenvironment in order to augment responses to existin...

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Bibliografiske detaljer
Udgivet i:Hemasphere
Main Authors: Swan, Dawn, Gurney, Mark, Krawczyk, Janusz, Ryan, Aideen E., O’Dwyer, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Wolters Kluwer Health 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7162079/
https://ncbi.nlm.nih.gov/pubmed/32309787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HS9.0000000000000350
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