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New developments in the treatment of multiple myeloma – clinical utility of daratumumab

Multiple myeloma is a clonal disorder of plasma cells that is currently considered incurable. CD38 is a 46 kDa type II transmembrane glycoprotein that is highly expressed on myeloma cells. Daratumumab is a first in-class human IgG1 monoclonal antibody that targets CD38, and has antimyeloma effects t...

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Podrobná bibliografie
Vydáno v:Biologics
Hlavní autoři: McEllistrim, Cian, Krawczyk, Janusz, O’Dwyer, Michael E
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395289/
https://ncbi.nlm.nih.gov/pubmed/28442888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BTT.S97633
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