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Ribonucleic acid sequence characterization by negative electron transfer dissociation mass spectrometry

Modified oligonucleotides represent a promising avenue for drug development, with small interfering RNAs (siRNA) and microRNAs gaining traction in the therapeutic market. Mass spectrometry (MS)-based analysis offers many benefits for characterizing modified nucleic acids. Negative electron transfer...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Anal Chem
Prif Awduron: Peters-Clarke, Trenton M., Quan, Qiuwen, Brademan, Dain R., Hebert, Alexander S., Westphall, Michael S., Coon, Joshua J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7161943/
https://ncbi.nlm.nih.gov/pubmed/32091202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b05388
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