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Rapid dynamics of signal-dependent transcriptional repression by Capicua
Optogenetic perturbations, live imaging, and time-resolved ChIP-seq assays in Drosophila embryos were used to dissect the ERK-dependent control of the HMG-box repressor Capicua (Cic), which plays critical roles in development and is deregulated in human spinocerebellar ataxia and cancers. We establi...
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| Publicado no: | Dev Cell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7161736/ https://ncbi.nlm.nih.gov/pubmed/32142631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.02.004 |
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