Melatonin up‐regulates bone marrow mesenchymal stem cells osteogenic action but suppresses their mediated osteoclastogenesis via MT(2)‐inactivated NF‐κB pathway

BACKGROUND AND PURPOSE: Melatonin is a neurohormone involved in bone homeostasis. Melatonin directs bone remodelling and the role of bone marrow mesenchymal stem cells (BMMSCs) in the regulating melatonin‐mediated bone formation–resorption balance remains undefined. EXPERIMENTAL APPROACH: Osteoporos...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Br J Pharmacol
Auteurs principaux: Zhou, Yi, Wang, Chaowei, Si, Jinyan, Wang, Baixiang, Zhang, Denghui, Ding, Ding, Zhang, Jian, Wang, Huiming
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Research Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7161576/
https://ncbi.nlm.nih.gov/pubmed/31900938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14972
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires