Donecopride, a Swiss army knife with potential against Alzheimer's disease

BACKGROUND AND PURPOSE: We recently identified donecopride as a pleiotropic compound able to inhibit AChE and to activate 5‐HT(4) receptors. Here, we have assessed the potential therapeutic effects of donecopride in treating Alzheimer's disease (AD). EXPERIMENTAL APPROACH: We used two in vivo a...

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Detalles Bibliográficos
Publicado en:Br J Pharmacol
Autores principales: Rochais, Christophe, Lecoutey, Cédric, Hamidouche, Katia, Giannoni, Patrizia, Gaven, Florence, Cem, Eleazere, Mignani, Serge, Baranger, Kevin, Freret, Thomas, Bockaert, Joël, Rivera, Santiago, Boulouard, Michel, Dallemagne, Patrick, Claeysen, Sylvie
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7161555/
https://ncbi.nlm.nih.gov/pubmed/31881553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14964
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