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Cetuximab PET delineated changes in cellular distribution of EGFR upon dasatinib treatment in triple negative breast cancer

BACKGROUND: At least 50% of triple negative breast cancer (TNBC) overexpress the epidermal growth factor receptor, EGFR, which paved the way for clinical trials investigating its blockade. Outcomes remained dismal stemming from mechanisms of resistance particularly the nuclear cycling of EGFR, which...

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發表在:Breast Cancer Res
Main Authors: McKnight, Brooke N., Kim, Seongho, Boerner, Julie L., Viola, Nerissa T.
格式: Artigo
語言:Inglês
出版: BioMed Central 2020
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160960/
https://ncbi.nlm.nih.gov/pubmed/32295603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-020-01270-1
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