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Monitoring Src status after dasatinib treatment in HER2+ breast cancer with (89)Zr-trastuzumab PET imaging

BACKGROUND: De novo or acquired resistance in breast cancer leads to treatment failures and disease progression. In human epidermal growth factor receptor 2 (HER2)-positive (HER2+) breast cancer, Src, a non-receptor tyrosine kinase, is identified as a major mechanism of trastuzumab resistance, with...

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Bibliografische gegevens
Gepubliceerd in:Breast Cancer Res
Hoofdauteurs: McKnight, Brooke N., Viola-Villegas, Nerissa T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203283/
https://ncbi.nlm.nih.gov/pubmed/30359299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-018-1055-2
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