Imaging EGFR and HER3 through (89)Zr-labeled MEHD7945A (Duligotuzumab)

Tumor resistance to treatment paved the way toward the development of single agent drugs that target multiple molecular signatures amplified within the malignancy. The discovered crosstalk between EGFR and HER3 as well as the role of HER3 in mediating EGFR resistance made these two receptor tyrosine...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: McKnight, Brooke N., Kuda-Wedagedara, Akhila N. W., Sevak, Kuntal K., Abdel-Atti, Dalya, Wiesend, Wendy N., Ku, Anson, Selvakumar, Dakshnamurthy, Carlin, Sean D., Lewis, Jason S., Viola-Villegas, Nerissa T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998059/
https://ncbi.nlm.nih.gov/pubmed/29899472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27454-6
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