Imaging EGFR and HER3 through (89)Zr-labeled MEHD7945A (Duligotuzumab)

Tumor resistance to treatment paved the way toward the development of single agent drugs that target multiple molecular signatures amplified within the malignancy. The discovered crosstalk between EGFR and HER3 as well as the role of HER3 in mediating EGFR resistance made these two receptor tyrosine...

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Pubblicato in:Sci Rep
Autori principali: McKnight, Brooke N., Kuda-Wedagedara, Akhila N. W., Sevak, Kuntal K., Abdel-Atti, Dalya, Wiesend, Wendy N., Ku, Anson, Selvakumar, Dakshnamurthy, Carlin, Sean D., Lewis, Jason S., Viola-Villegas, Nerissa T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998059/
https://ncbi.nlm.nih.gov/pubmed/29899472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27454-6
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