LNK promotes the growth and metastasis of triple negative breast cancer via activating JAK/STAT3 and ERK1/2 pathway

BACKGROUND: LNK adaptor protein is a crucial regulator of normal hematopoiesis, which down-regulates activated tyrosine kinases at the cell surface resulting in an antitumor effect. To date, little studies have examined activities of LNK in solid tumors except ovarian cancer. METHODS: Clinical tissu...

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Publicat a:Cancer Cell Int
Autors principals: Lv, Jianxin, Yu, Wei, Zhang, Yanan, Cao, Xinhua, Han, Lifei, Hu, Haolin, Wang, Chenfei
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Primary Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160949/
https://ncbi.nlm.nih.gov/pubmed/32322171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01197-9
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