Whole-genome genotyping and resequencing reveal the association of a deletion in the complex interferon alpha gene cluster with hypothyroidism in dogs

BACKGROUND: Hypothyroidism is a common complex endocrinopathy that typically has an autoimmune etiology, and it affects both humans and dogs. Genetic and environmental factors are both known to play important roles in the disease development. In this study, we sought to identify the genetic risk fac...

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Publicat a:BMC Genomics
Autors principals: Bianchi, Matteo, Rafati, Nima, Karlsson, Åsa, Murén, Eva, Rubin, Carl-Johan, Sundberg, Katarina, Andersson, Göran, Kämpe, Olle, Hedhammar, Åke, Lindblad-Toh, Kerstin, Rosengren Pielberg, Gerli
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160888/
https://ncbi.nlm.nih.gov/pubmed/32299354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-020-6700-3
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