Whole-genome genotyping and resequencing reveal the association of a deletion in the complex interferon alpha gene cluster with hypothyroidism in dogs

BACKGROUND: Hypothyroidism is a common complex endocrinopathy that typically has an autoimmune etiology, and it affects both humans and dogs. Genetic and environmental factors are both known to play important roles in the disease development. In this study, we sought to identify the genetic risk fac...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Bianchi, Matteo, Rafati, Nima, Karlsson, Åsa, Murén, Eva, Rubin, Carl-Johan, Sundberg, Katarina, Andersson, Göran, Kämpe, Olle, Hedhammar, Åke, Lindblad-Toh, Kerstin, Rosengren Pielberg, Gerli
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160888/
https://ncbi.nlm.nih.gov/pubmed/32299354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-020-6700-3
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