High activation and skewed T cell differentiation are associated with low IL‐17A levels in a hu‐PBL‐NSG‐SGM3 mouse model of HIV infection

The humanized NOD/SCID/IL‐2 receptor γ‐chain(null) (NSG) mouse model has been widely used for the study of HIV pathogenesis. Here, NSG mice with transgenic expression of human stem cell factor (SCF), granulocyte–macrophage colony‐stimulating factor (GM‐CSF) and interleukin (IL)‐3 (NSG‐SGM3) were inj...

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Detalhes bibliográficos
Publicado no:Clin Exp Immunol
Main Authors: Perdomo‐Celis, F., Medina‐Moreno, S., Davis, H., Bryant, J., Taborda, N. A., Rugeles, M. T., Kottilil, S., Zapata, J. C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160662/
https://ncbi.nlm.nih.gov/pubmed/31951011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13416
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