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Resveratrol attenuates hypoxia-induced neuronal cell death, inflammation and mitochondrial oxidative stress by modulation of TRPM2 channel
Hypoxia (HYPX) induced-overload Ca(2+) entry results in increase of mitochondrial oxidative stress, inflammation and apoptosis in several neurons. Ca(2+) permeable TRPM2 channel was gated by ADP-ribose (ADPR) and reactive oxygen species (ROS), although its activity was modulated in HYPX-exposed neur...
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| Publicado no: | Sci Rep |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7160154/ https://ncbi.nlm.nih.gov/pubmed/32296107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63577-5 |
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