The Biogenesis, Biology, and Clinical Significance of Exosomal PD-L1 in Cancer

The exosome serves as a trafficking vehicle for transport of programmed death-ligand 1 (PD-L1) into receptor cells. In tumor microenvironment, distant tumor cells can remotely attack activated T cells by exosomal PD-L1. Here, we summerize the biogenesis and transport process of exosomal PD-L1. Then,...

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Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: Tang, Yanyan, Zhang, Ping, Wang, Yumin, Wang, Jinpeng, Su, Min, Wang, Ying, Zhou, Lianqing, Zhou, Jumei, Xiong, Wei, Zeng, Zhaoyang, Zhou, Yujuan, Nie, Shaolin, Liao, Qianjin
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7158891/
https://ncbi.nlm.nih.gov/pubmed/32322256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00604
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