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Systems Vaccinology for a Live Attenuated Tularemia Vaccine Reveals Unique Transcriptional Signatures That Predict Humoral and Cellular Immune Responses

Background: Tularemia is a potential biological weapon due to its high infectivity and ease of dissemination. This study aimed to characterize the innate and adaptive responses induced by two different lots of a live attenuated tularemia vaccine and compare them to other well-characterized viral vac...

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Detalhes bibliográficos
Publicado no:Vaccines (Basel)
Main Authors: Natrajan, Muktha S., Rouphael, Nadine, Lai, Lilin, Kazmin, Dmitri, Jensen, Travis L., Weiss, David S., Ibegbu, Chris, Sztein, Marcelo B., Hooper, William F., Hill, Heather, Anderson, Evan J., Johnson, Robert, Sanz, Patrick, Pulendran, Bali, Goll, Johannes B., Mulligan, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7158697/
https://ncbi.nlm.nih.gov/pubmed/31878161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8010004
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