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Systems Vaccinology for a Live Attenuated Tularemia Vaccine Reveals Unique Transcriptional Signatures That Predict Humoral and Cellular Immune Responses

Background: Tularemia is a potential biological weapon due to its high infectivity and ease of dissemination. This study aimed to characterize the innate and adaptive responses induced by two different lots of a live attenuated tularemia vaccine and compare them to other well-characterized viral vac...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Vaccines (Basel)
Hauptverfasser: Natrajan, Muktha S., Rouphael, Nadine, Lai, Lilin, Kazmin, Dmitri, Jensen, Travis L., Weiss, David S., Ibegbu, Chris, Sztein, Marcelo B., Hooper, William F., Hill, Heather, Anderson, Evan J., Johnson, Robert, Sanz, Patrick, Pulendran, Bali, Goll, Johannes B., Mulligan, Mark J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7158697/
https://ncbi.nlm.nih.gov/pubmed/31878161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8010004
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