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Intrathecal liposomal cytarabine plus systemic therapy versus systemic chemotherapy alone for newly diagnosed leptomeningeal metastasis from breast cancer

BACKGROUND: DEPOSEIN (NCT01645839) was a randomized open-label phase III study to explore the role of intrathecal chemotherapy in patients with newly diagnosed leptomeningeal metastasis (LM), a common manifestation of breast cancer. METHODS: Patients with newly diagnosed LM defined by tumor cells in...

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Publicat a:Neuro Oncol
Autors principals: Le Rhun, Emilie, Wallet, Jennifer, Mailliez, Audrey, Le Deley, Marie Cecile, Rodrigues, Isabelle, Boulanger, Thomas, Lorgis, Veronique, Barrière, Jerome, Robin, Yves Marie, Weller, Michael, Bonneterre, Jacques
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7158648/
https://ncbi.nlm.nih.gov/pubmed/31637444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz201
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