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OS10.4 Intrathecal liposomal cytarabine plus systemic therapy versus systemic chemotherapy alone for leptomeningeal metastasis from breast cancer - a randomized study. Final results

BACKGROUND: Leptomeningeal metastasis (LM) is a common manifestation in metastatic breast cancer. Standards of care remain controversial, notably intrathecal pharmacotherapy. MATERIAL AND METHODS: DEPO-SEIN was a randomized open-label phase III study to explore the addition of intrathecal liposomal...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Le Rhun, E, Wallet, J, Mailliez, A, Le Deley, M, Rodrigues, I, Boulanger, T, Lorgis, V, Barriere, J, Robin, Y, Weller, M, Bonneterre, J
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795587/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz126.070
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