Transcriptional dysregulation in developing trigeminal sensory neurons in the LgDel mouse model of DiGeorge 22q11.2 deletion syndrome

LgDel mice, which model the heterozygous deletion of genes at human chromosome 22q11.2 associated with DiGeorge/22q11.2 deletion syndrome (22q11DS), have cranial nerve and craniofacial dysfunction as well as disrupted suckling, feeding and swallowing, similar to key 22q11DS phenotypes. Divergent tri...

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Enregistré dans:
Détails bibliographiques
Publié dans:Hum Mol Genet
Auteurs principaux: Maynard, Thomas M, Horvath, Anelia, P Bernot, James, Karpinski, Beverly A, Tavares, Andre L P, Shah, Ankita, Zheng, Qianqian, Spurr, Liam, Olender, Jacqueline, Moody, Sally A, Fraser, Claire M, LaMantia, Anthony-S, Lee, Norman H
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
General Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7158380/
https://ncbi.nlm.nih.gov/pubmed/32047912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa024
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