Transcriptional dysregulation in developing trigeminal sensory neurons in the LgDel mouse model of DiGeorge 22q11.2 deletion syndrome

LgDel mice, which model the heterozygous deletion of genes at human chromosome 22q11.2 associated with DiGeorge/22q11.2 deletion syndrome (22q11DS), have cranial nerve and craniofacial dysfunction as well as disrupted suckling, feeding and swallowing, similar to key 22q11DS phenotypes. Divergent tri...

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Bibliografski detalji
Izdano u:Hum Mol Genet
Glavni autori: Maynard, Thomas M, Horvath, Anelia, P Bernot, James, Karpinski, Beverly A, Tavares, Andre L P, Shah, Ankita, Zheng, Qianqian, Spurr, Liam, Olender, Jacqueline, Moody, Sally A, Fraser, Claire M, LaMantia, Anthony-S, Lee, Norman H
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
General Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7158380/
https://ncbi.nlm.nih.gov/pubmed/32047912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa024
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