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DMD carrier model with mosaic dystrophin expression in the heart reveals complex vulnerability to myocardial injury

Duchenne muscular dystrophy (DMD) is a devastating neuromuscular disease that causes progressive muscle wasting and cardiomyopathy. This X-linked disease results from mutations of the DMD allele on the X-chromosome resulting in the loss of expression of the protein dystrophin. Dystrophin loss causes...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Meyers, Tatyana A, Heitzman, Jackie A, Townsend, DeWayne
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7158376/
https://ncbi.nlm.nih.gov/pubmed/31976522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa015
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