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Baseline levels of dynamic CD4(+) T cell adhesion to MAdCAM-1 correlate with clinical response to vedolizumab treatment in ulcerative colitis: a cohort study

BACKGROUND: While the number of therapeutic options for treating inflammatory bowel diseases (IBD) is increasing, evidence for rational treatment decisions is scarce in many cases. In particular, appropriate biomarkers to predict the response to the anti-α4β7 integrin antibody vedolizumab are curren...

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Bibliografski detalji
Izdano u:BMC Gastroenterol
Glavni autori: Allner, Clarissa, Melde, Michaela, Becker, Emily, Fuchs, Friederike, Mühl, Laura, Klenske, Entcho, Müller, Lisa, Morgenstern, Nadine, Fietkau, Konstantin, Hirschmann, Simon, Atreya, Raja, Atreya, Imke, Neurath, Markus F., Zundler, Sebastian
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7158080/
https://ncbi.nlm.nih.gov/pubmed/32293299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-020-01253-8
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