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Downregulation of A20 Expression Increases the Immune Response and Apoptosis and Reduces Virus Production in Cells Infected by the Human Respiratory Syncytial Virus

Human respiratory syncytial virus (HRSV) causes severe lower respiratory tract infections in infants, the elderly, and immunocompromised adults. Regulation of the immune response against HRSV is crucial to limiting virus replication and immunopathology. The A20/TNFAIP3 protein is a negative regulato...

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Detalhes bibliográficos
Publicado no:Vaccines (Basel)
Main Authors: Martín-Vicente, María, González-Sanz, Rubén, Cuesta, Isabel, Monzón, Sara, Resino, Salvador, Martínez, Isidoro
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7157707/
https://ncbi.nlm.nih.gov/pubmed/32102364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8010100
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