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Development of an IL-17A DNA Vaccine to Treat Systemic Lupus Erythematosus in Mice
The interleukin-17 (IL-17) family, especially IL-17A, plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). This study developed an IL-17A epitope vaccine to treat SLE in NZBWF1 and MRL/lpr mouse models. A plasmid vector encoding a hepatitis B core (HBc)-IL-17A epitope f...
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| 出版年: | Vaccines (Basel) |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7157613/ https://ncbi.nlm.nih.gov/pubmed/32059488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8010083 |
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