Establishment of a Plasmid-Based Reverse Genetics System for the Cell Culture-Adapted Hepatitis E Virus Genotype 3c Strain 47832c

The hepatitis E virus (HEV) causes acute and chronic hepatitis in humans. Investigation of HEV replication is hampered by the lack of broadly applicable, efficient cell culture systems and tools for site-directed mutagenesis of HEV. The cell culture-adapted genotype 3c strain 47832c, which represent...

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Vydáno v:Pathogens
Hlavní autoři: Scholz, Johannes, Bächlein, Christine, Gadicherla, Ashish K., Falkenhagen, Alexander, Tausch, Simon H., Johne, Reimar
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7157446/
https://ncbi.nlm.nih.gov/pubmed/32106549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens9030157
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