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Nuclear factor IX promotes glioblastoma development through transcriptional activation of Ezrin

Enhanced migration is pivotal for the malignant development of glioblastoma (GBM), but the underlying molecular mechanism that modulates the migration of the GBM cells remains obscure. Here we show that nuclear factor IX (NFIX) is significantly upregulated in human GBM lesions compared with normal o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncogenesis
Hauptverfasser: Liu, Zhuohao, Ge, Ruixiang, Zhou, Jiayi, Yang, Xinzhi, Cheng, Kenneth King-yip, Tao, Jingli, Wu, Dinglan, Mao, Jie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156762/
https://ncbi.nlm.nih.gov/pubmed/32291386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-0223-2
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