Adrenergic stress constrains the development of anti-tumor immunity and abscopal responses following local radiation

The abscopal effect following ionizing radiation therapy (RT) is considered to be a rare event. This effect does occur more frequently when combined with other therapies, including immunotherapy. Here we demonstrate that the frequency of abscopal events following RT alone is highly dependent upon th...

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Udgivet i:Nat Commun
Main Authors: Chen, Minhui, Qiao, Guanxi, Hylander, Bonnie L., Mohammadpour, Hemn, Wang, Xiang-Yang, Subjeck, John R., Singh, Anurag K., Repasky, Elizabeth A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156731/
https://ncbi.nlm.nih.gov/pubmed/32286326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15676-0
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