Anticancer effects of chemokine-directed antigen delivery to a cross-presenting dendritic cell subset with immune checkpoint blockade

BACKGROUND: Cancer peptide vaccines show only marginal effects against cancers. Immune checkpoint inhibitors (ICIs) show significant curative effects in certain types of cancers, but the response rate is still limited. In this study, we aim to improve cancer peptide vaccination by targeting Ag pepti...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Br J Cancer
Egile Nagusiak: Mizumoto, Yuki, Hemmi, Hiroaki, Katsuda, Masahiro, Miyazawa, Motoki, Kitahata, Yuji, Miyamoto, Atsushi, Nakamori, Mikihito, Ojima, Toshiyasu, Matsuda, Kenji, Nakamura, Masaki, Hayata, Keiji, Fukuda-Ohta, Yuri, Sugiyama, Masanaka, Ohta, Tomokazu, Orimo, Takashi, Okura, Soichiro, Sasaki, Izumi, Tamada, Koji, Yamaue, Hiroki, Kaisho, Tsuneyasu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156711/
https://ncbi.nlm.nih.gov/pubmed/32066911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0757-2
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