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Ribosome profiling at isoform level reveals evolutionary conserved impacts of differential splicing on the proteome

The differential production of transcript isoforms from gene loci is a key cellular mechanism. Yet, its impact in protein production remains an open question. Here, we describe ORQAS (ORF quantification pipeline for alternative splicing), a pipeline for the translation quantification of individual t...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Reixachs-Solé, Marina, Ruiz-Orera, Jorge, Albà, M. Mar, Eyras, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156646/
https://ncbi.nlm.nih.gov/pubmed/32286305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15634-w
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