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Differentiated evolutionary rates in alternative exons and the implications for splicing regulation

BACKGROUND: Alternatively spliced exons play an important role in the diversification of gene function in most metazoans and are highly regulated by conserved motifs in exons and introns. Two contradicting properties have been associated to evolutionary conserved alternative exons: higher sequence c...

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Autores principales: Plass, Mireya, Eyras, Eduardo
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1543662/
https://ncbi.nlm.nih.gov/pubmed/16792801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-6-50
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