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Differentiated evolutionary rates in alternative exons and the implications for splicing regulation

BACKGROUND: Alternatively spliced exons play an important role in the diversification of gene function in most metazoans and are highly regulated by conserved motifs in exons and introns. Two contradicting properties have been associated to evolutionary conserved alternative exons: higher sequence c...

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Bibliographic Details
Main Authors: Plass, Mireya, Eyras, Eduardo
Format: Artigo
Language:Inglês
Published: BioMed Central 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1543662/
https://ncbi.nlm.nih.gov/pubmed/16792801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-6-50
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