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Differentiated evolutionary rates in alternative exons and the implications for splicing regulation

BACKGROUND: Alternatively spliced exons play an important role in the diversification of gene function in most metazoans and are highly regulated by conserved motifs in exons and introns. Two contradicting properties have been associated to evolutionary conserved alternative exons: higher sequence c...

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Detalhes bibliográficos
Main Authors: Plass, Mireya, Eyras, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1543662/
https://ncbi.nlm.nih.gov/pubmed/16792801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-6-50
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