Quantifying the heterogeneity of macromolecular machines by mass photometry

Sample purity is central to in vitro studies of protein function and regulation, and to the efficiency and success of structural studies using techniques such as x-ray crystallography and cryo-electron microscopy (cryo-EM). Here, we show that mass photometry (MP) can accurately characterize the hete...

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Publicado en:Nat Commun
Autores principales: Sonn-Segev, Adar, Belacic, Katarina, Bodrug, Tatyana, Young, Gavin, VanderLinden, Ryan T., Schulman, Brenda A., Schimpf, Johannes, Friedrich, Thorsten, Dip, Phat Vinh, Schwartz, Thomas U., Bauer, Benedikt, Peters, Jan-Michael, Struwe, Weston B., Benesch, Justin L. P., Brown, Nicholas G., Haselbach, David, Kukura, Philipp
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156492/
https://ncbi.nlm.nih.gov/pubmed/32286308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15642-w
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