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Capturing the primordial Kras mutation initiating urethane carcinogenesis
The environmental carcinogen urethane exhibits a profound specificity for pulmonary tumors driven by an oncogenic Q(61)L/R mutation in the gene Kras. Similarly, the frequency, isoform, position, and substitution of oncogenic RAS mutations are often unique to human cancers. To elucidate the principle...
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| I publikationen: | Nat Commun |
|---|---|
| Huvudupphovsmän: | , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Nature Publishing Group UK
2020
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7156420/ https://ncbi.nlm.nih.gov/pubmed/32286309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15660-8 |
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