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The dynactin subunit DCTN1 controls osteoclastogenesis via the Cdc42/PAK2 pathway
Osteoclasts (OCs), cells specialized for bone resorption, are generated from monocyte/macrophage precursors by a differentiation process governed by RANKL. Here, we show that DCTN1, a key component of the dynactin complex, plays important roles in OC differentiation. The expression of DCTN1 was upre...
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| 出版年: | Exp Mol Med |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7156411/ https://ncbi.nlm.nih.gov/pubmed/32210358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-020-0406-0 |
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